{"id":14294,"date":"2025-09-12T07:59:15","date_gmt":"2025-09-12T05:59:15","guid":{"rendered":"https:\/\/sublio.com\/scientific-results\/"},"modified":"2026-11-04T02:36:04","modified_gmt":"2026-11-04T01:36:04","slug":"scientific-results","status":"publish","type":"page","link":"https:\/\/sublio.com\/en\/scientific-results\/","title":{"rendered":"Scientific results"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"14294\" class=\"elementor elementor-14294 elementor-1321\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ee9779e e-flex e-con-boxed e-con e-parent\" data-id=\"ee9779e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-75f1ca7 elementor-widget elementor-widget-text-editor\" data-id=\"75f1ca7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>SCIENTIFIC RESULTS<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8521809 elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"8521809\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Demonstration <span style=\"font-style:italic\">through science<\/span>.<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd04d64 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget-tablet__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"cd04d64\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Twelve independent biological studies that objectively demonstrate the high efficacy of Hyperionisation\u00ae on the skin, the hallmark of exceptional hospitality.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4368276 e-flex e-con-boxed e-con e-parent\" data-id=\"4368276\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f913dc elementor-widget elementor-widget-text-editor\" data-id=\"4f913dc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>AT THE HEART OF WELLNESS<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c522566 elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"c522566\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A standard of proof, worthy of your <span style=\"font-style:italic\">establishment<\/span>.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1035398 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget-tablet__width-inherit sublio-aere elementor-widget elementor-widget-text-editor\" data-id=\"1035398\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>These studies pursue a precise aim: to assess, under recognised laboratory protocols, what hyperionic water brings to the skin, within the world of spas and prestige hospitality.<\/p><p>They focus on what builds the reputation of a great house: the quality of the skin and the comfort felt by every guest.<\/p><p>For management, they provide a certainty: the elevated experience offered to your clientele rests on results obtained in the laboratory, not on a mere promise.<\/p><p><span style=\"font-weight:600\">Hydration, barrier function, skin comfort: what your guests feel, the laboratories have measured.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-eb2c8c1 e-flex e-con-boxed e-con e-parent\" data-id=\"eb2c8c1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4ad209b elementor-widget elementor-widget-text-editor\" data-id=\"4ad209b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>INDEPENDENT VALIDATION<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-63c15e8 elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"63c15e8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A commitment to <span style=\"font-style:italic\">transparency<\/span>.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-786059b elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget-tablet__width-inherit sublio-aere elementor-widget elementor-widget-text-editor\" data-id=\"786059b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Sublio hyperionic water stems from an exceptional technology, developed to the most exacting scientific criteria.<\/p><p>Since its very first installations, Sublio has entrusted the validation of its technology to independent scientific bodies.<\/p><p>Its distinctive characteristics in contact with the skin have been documented by leading independent laboratories.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ceffc3a e-flex e-con-boxed e-con e-parent\" data-id=\"ceffc3a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3514c7d elementor-widget elementor-widget-text-editor\" data-id=\"3514c7d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>TWO COMPLEMENTARY APPROACHES<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-804d3eb elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"804d3eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A dual reading, biological and <span style=\"font-style:italic\">transcriptomic<\/span>.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b3ca0f elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget-tablet__width-inherit sublio-aere elementor-widget elementor-widget-text-editor\" data-id=\"5b3ca0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>It sheds light on the effects of Sublio technology on the skin, far beyond mere sensation.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a995c42 e-con-full sublio-cartes e-flex e-con e-child\" data-id=\"a995c42\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-39f7555 elementor-widget elementor-widget-text-editor\" data-id=\"39f7555\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-etude\"><p class=\"se-num\">Ex vivo and in vivo<\/p><h3 class=\"se-titre\">Studies of the highest calibre<\/h3><p class=\"se-p\">Conducted on ex vivo human skin explants and on human skin in vivo, they measure with laboratory precision the visible effects of hyperionic water on the skin.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-55ac37e elementor-widget elementor-widget-text-editor\" data-id=\"55ac37e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-etude\"><p class=\"se-num\">Transcriptomics<\/p><h3 class=\"se-titre\">Transcriptomic analyses<\/h3><p class=\"se-p\">They reveal the variations in expression of specific messenger RNAs after exposure to Sublio hyperionic water, and highlight the finesse of its interaction with the epidermis.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0458e78 e-flex e-con-boxed e-con e-parent\" data-id=\"0458e78\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4550a96 elementor-widget elementor-widget-text-editor\" data-id=\"4550a96\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>THE STUDIES<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-02a651e elementor-widget__width-initial elementor-widget-tablet__width-inherit elementor-widget-mobile__width-inherit elementor-widget elementor-widget-heading\" data-id=\"02a651e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Six years of scientific research, one unbroken <span style=\"font-style:italic\">thread<\/span>.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0896702 elementor-widget__width-initial elementor-widget-mobile__width-inherit elementor-widget-tablet__width-inherit sublio-aere elementor-widget elementor-widget-text-editor\" data-id=\"0896702\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Presented from the most recent to the earliest, from 2025 back to 2019, they reveal the full breadth of Sublio\u2019s field of action.<\/p><p>Some protocols rely on demanding laboratory models, such as ex vivo psoriatic skin: they make it possible to measure the skin\u2019s response with precision.<\/p><p class=\"sublio-dispo\">The laboratories\u2019 summary notes are available in French and English.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-04ba537 elementor-widget elementor-widget-text-editor\" data-id=\"04ba537\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul class=\"sublio-chiffres\"><li><strong>12<\/strong><span>independent biological studies<\/span><\/li><li><strong>3<\/strong><span>methods: ex vivo, in vivo, transcriptomics<\/span><\/li><li><strong>20<\/strong><span>volunteers in the in vivo clinical study<\/span><\/li><li><strong>2<\/strong><span>languages available: French and English<\/span><\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e5c5b19 e-con-full sublio-frise e-flex e-con e-child\" data-id=\"e5c5b19\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-407010f elementor-widget elementor-widget-text-editor\" data-id=\"407010f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">12<\/span><span class=\"sj-an\">2025<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 12<\/p><h3 class=\"se-titre\">Clinical study: hydration and barrier function in 20 volunteers<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Hydration and barrier function significantly strengthened, skin redness significantly reduced.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>In vivo clinical study, two daily applications over 4 days, mains water and hyperionic mains water<\/dd><\/div><div><dt>Objective<\/dt><dd>Measure the effect of hyperionic water on skin hydration and barrier function<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-12_Hydratation-in-vivo_NV-FR_2025_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-12_Hydratation-in-vivo_NV-GB_2025_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e8b22b3 elementor-widget elementor-widget-text-editor\" data-id=\"e8b22b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">11<\/span><span class=\"sj-an\">2024<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 11<\/p><h3 class=\"se-titre\">Analytical and bacteriological control of a mineral water after Hyperionisation\u00ae<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Composition and bacteriological quality strictly unchanged: nothing is added, nothing is removed.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Physico-chemical and bacteriological analyses<\/dd><\/div><div><dt>Objective<\/dt><dd>Verify that Sublio alters neither the composition nor the bacteriological quality of the water<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-11_Etude-Analytique-et-bacteriologie_NV-FR_2024_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-11_Etude-Analytique-et-bacteriologie_NV-GB_2024_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2adddc7 elementor-widget elementor-widget-text-editor\" data-id=\"2adddc7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">10<\/span><span class=\"sj-an\">2023<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 10<\/p><h3 class=\"se-titre\">Enhancement of a cosmetic active ingredient: retinol<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>A markedly more active retinol formulation, with an earlier onset, whether itself hyperionic or preceded by a hyperionic thermal water.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Ex vivo human skin explants, histological analysis at 3 and 6 days<\/dd><\/div><div><dt>Objective<\/dt><dd>Assess the effect of Hyperionisation\u00ae on the activity of a retinol formulation, applied alone or after a hyperionic thermal water<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-10-_Formulation_NV-FR-_-2023_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-10-_Formulation_NV-GB-_-2023_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e16b446 elementor-widget elementor-widget-text-editor\" data-id=\"e16b446\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">09<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 09<\/p><h3 class=\"se-titre\">Hyperionic seawater and mains water: a comparative genomic study<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>In both cases, stimulation of the genes associated with skin protection and renewal.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Transcriptomic analysis on ex vivo human skin explants<\/dd><\/div><div><dt>Objective<\/dt><dd>Study the compatibility of the Sublio process with waters of very different natures<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-09-_-Genomique-D3_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-09-_-Genomique-D3_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d371b0 elementor-widget elementor-widget-text-editor\" data-id=\"7d371b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">08<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 08<\/p><h3 class=\"se-titre\">Hyperionic mains water and thermal water: a comparative genomic study<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Hyperionic thermal water proves more active on the skin than raw thermal water.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Transcriptomic analysis on ex vivo human skin explants<\/dd><\/div><div><dt>Objective<\/dt><dd>Compare raw thermal water with hyperionic thermal water<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-08-_-Genomique-D2_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-08-_-Genomique-D2_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58149ed elementor-widget elementor-widget-text-editor\" data-id=\"58149ed\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">07<\/span><span class=\"sj-num\">06<\/span><span class=\"sj-num\">05<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Studies 05, 06 and 07<\/p><h3 class=\"se-titre\">Assessment on a psoriatic skin model, in three parts<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Reduction of three major markers of psoriatic skin and, significantly, of one inflammatory marker.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Ex vivo psoriatic human skin explants, daily treatment over 4 days<\/dd><\/div><div><dt>Objective<\/dt><dd>Assess the effect of hyperionic water on the characteristic markers of psoriatic skin<\/dd><\/div><\/dl><div class=\"se-pdf se-pdf-multi\"><span class=\"se-pdf-t\">Read the summary<\/span><span class=\"se-pdf-l\">Fran\u00e7ais<\/span><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-05-_-Psoriasis-part-1_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">05<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-06-_-Psoriasis-part-12_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">06<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-07-_-Psoriasis-part-2_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">07<\/a><span class=\"se-pdf-l\">English<\/span><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-05-_-Psoriasis-part-1_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">05<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-06-_-Psoriasis-part-12_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">06<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-07-_-Psoriasis-part-2_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">07<\/a><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4f7abb3 elementor-widget elementor-widget-text-editor\" data-id=\"4f7abb3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">04<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 04<\/p><h3 class=\"se-titre\">Skin absorption of trace elements from a hyperionic seawater<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Hyperionic water promotes the skin penetration of beneficial trace elements.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Human skin explants on Franz cells<\/dd><\/div><div><dt>Objective<\/dt><dd>Measure the cutaneous bioavailability of minerals<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-04_-PTC-eau-de-mer_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-04_-PTC-eau-de-mer_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6916fc6 elementor-widget elementor-widget-text-editor\" data-id=\"6916fc6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">03<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 03<\/p><h3 class=\"se-titre\">Genomic synthesis across three donors: hyperionic mains water<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Favourable gene response: hydration, regeneration, soothing.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Transcriptomic analysis, three studies combined<\/dd><\/div><div><dt>Objective<\/dt><dd>Objectively assess the molecular impact of mains water treated by Sublio<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-03-_-Genomique-1-2-3_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-03-_-Genomique-1-2-3_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b3b8724 elementor-widget elementor-widget-text-editor\" data-id=\"b3b8724\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">02<\/span><span class=\"sj-an\">2021<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 02<\/p><h3 class=\"se-titre\">Transcriptomic study: mains water and hyperionic mains water<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Evidence of biological actions involved in hydration, regeneration and skin protection.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Messenger RNA analysis on ex vivo human skin explants<\/dd><\/div><div><dt>Objective<\/dt><dd>Identify the genes modulated by exposure to hyperionic water<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-02-_-Genomique-D1_NV-FR-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-02-_-Genomique-D1_NV-GB-_-2021_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-04959bd elementor-widget elementor-widget-text-editor\" data-id=\"04959bd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"sublio-jalon\"><div class=\"sj-rep\"><span class=\"sj-num\">01<\/span><span class=\"sj-an\">2019<\/span><\/div><div class=\"sublio-etude\"><p class=\"se-num\">Study 01<\/p><h3 class=\"se-titre\">Hydrating and restorative activity of hyperionic water<\/h3><div class=\"se-bref\"><span>In brief<\/span><p>Strengthened skin barrier, enhanced cell cohesion, clearly visible hydration.<\/p><\/div><dl class=\"se-dl se-2col\"><div><dt>Method<\/dt><dd>Ex vivo human skin explants<\/dd><\/div><div><dt>Objective<\/dt><dd>Observe the effect of Hyperionisation\u00ae on the skin barrier and cell differentiation<\/dd><\/div><\/dl><p class=\"se-pdf\">Read the summary<a href=\"\/wp-content\/uploads\/2026\/02\/Etude-01-_-Hydratation_NV-FR-_-2029_web.pdf\" target=\"_blank\" rel=\"noopener\">Fran\u00e7ais<\/a><a href=\"\/wp-content\/uploads\/2026\/02\/Etude-01-_-Hydratation_NV-GB-_-2029_web.pdf\" target=\"_blank\" rel=\"noopener\">English<\/a><\/p><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-38a4bcd elementor-widget elementor-widget-text-editor\" data-id=\"38a4bcd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p class=\"sublio-fin\">The documents above are summary notes, written by the laboratories to make their work intelligible to all. 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data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2689566 elementor-widget elementor-widget-text-editor\" data-id=\"2689566\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>A PROVEN INNOVATION<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6759bf0 elementor-widget elementor-widget-image\" data-id=\"6759bf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"236\" height=\"59\" src=\"https:\/\/sublio.com\/wp-content\/uploads\/2026\/04\/picto-etudes-biologiques-sublio.svg\" class=\"attachment-medium_large size-medium_large wp-image-19331\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb95af9 elementor-widget elementor-widget-text-editor\" data-id=\"eb95af9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>12 independent biological studies.<\/p>\n<p>A patented process, trademarks protected internationally.<\/p>\n<p>World-renowned laboratories behind every result.<\/p>\n<p><span style=\"font-weight: 600;\">Sublio does not make promises,<br \/>Sublio demonstrates.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-01d205a elementor-align-center elementor-button-warning elementor-widget elementor-widget-button\" data-id=\"01d205a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"\/en\/feasibility-study\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Request your feasibility study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>SCIENTIFIC RESULTS Demonstration through science. Twelve independent biological studies that objectively demonstrate the high efficacy of Hyperionisation\u00ae on the skin, the hallmark of exceptional hospitality. AT THE HEART OF WELLNESS A standard of proof, worthy of your establishment. These studies pursue a precise aim: to assess, under recognised laboratory protocols, what hyperionic water brings to [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-14294","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Scientific results: twelve studies on hyperionic water | Sublio<\/title>\n<meta name=\"description\" content=\"Twelve independent studies, 2019 to 2025: hydration, barrier function, genomics, enhanced actives. Sublio does not make promises. 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